Friday, February 10, 2012

Severed Nerves Repaired and Restoring Function




This opens the door for rapid and successful nerve repair in humans which has never been possible and does not ever occur naturally.  It represents the first real therapeutic progress on nerves that I have seen.

It does not solve situations in which a lot of nerve tissue is lost or sadly those long since injured.

It looks like that freshly injured patients have a clear three day window in which to bring about a significant amount of actual healing and relinking of the nerves.  All leading to actual recovery of usage.



New procedure repairs severed nerves in minutes, restoring limb use in days or weeks
Team apply new procedure to rapidly induce nerve regeneration in mammals

American scientists believe a new procedure to repair severed nerves could result in patients recovering in days or weeks, rather than months or years. The team used a cellular mechanism similar to that used by many invertebrates to repair damage to nerve axons. Their results are published today in the Journal of Neuroscience Research.

"We have developed a procedure which can repair severed nerves within minutes so that the behavior they control can be partially restored within days and often largely restored within two to four weeks," said Professor George Bittner from the University of Texas. "If further developed in clinical trials this approach would be a great advance on current procedures that usually imperfectly restore lost function within months at best."

The team studied the mechanisms all animal cells use to repair damage to their membranes and focused on invertebrates, which have a superior ability to regenerate nerve axons compared to mammals. An axon is a long extension arising from a nerve cell body that communicates with other nerve cells or with muscles.

This research success arises from Bittner's discovery that nerve axons of invertebrates which have been severed from their cell body do not degenerate within days, as happens with mammals, but can survive for months, or even years.

The severed proximal nerve axon in invertebrates can also reconnect with its surviving distal nerve axon to produce much quicker and much better restoration of behaviour than occurs in mammals.

"Severed invertebrate nerve axons can reconnect proximal and distal ends of severed nerve axons within seven days, allowing a rate of behavioural recovery that is far superior to mammals," said Bittner. "In mammals the severed distal axonal stump degenerates within three days and it can take nerve growths from proximal axonal stumps months or years to regenerate and restore use of muscles or sensory areas, often with less accuracy and with much less function being restored."

The team described their success in applying this process to rats in two research papers published today. The team were able to repair severed sciatic nerves in the upper thigh, with results showing the rats were able to use their limb within a week and had much function restored within 2 to 4 weeks, in some cases to almost full function.

"We used rats as an experimental model to demonstrate how severed nerve axons can be repaired. Without our procedure, the return of nearly full function rarely comes close to happening," said Bittner. "The sciatic nerve controls all muscle movement of the leg of all mammals and this new approach to repairing nerve axons could almost-certainly be just as successful in humans."

To explore the long term implications and medical uses of this procedure, MD's and other scientist- collaborators at Harvard Medical School and Vanderbilt Medical School and Hospitals are conducting studies to obtain approval to begin clinical trials.

"We believe this procedure could produce a transformational change in the way nerve injuries are repaired," concluded Bittner.

3 comments:

Anonymous said...

Where's the link to the article? Why should we be asked to read your italicized version of it when we can read the original? Please post the sources for your articles.

Bob W Todd said...

I am reading this article about nerve healing and I need more information and contact with the people involveed.

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Here is my problem.

http://home.earthlink.net/~btodd75/naionhello.html
http://home.earthlink.net/~k7vhq/eyesuit.htm

Thank you so much,

Robert Wheeler Todd
San Jacinto, CA 92582

celia os said...

Excepcional filme para a época que foi produzido. A universalidade do cinema mudo, mesmo se não tivesse legendas consente com sua literatura visual a compreensão da estória. Lamento informá-lhes que ao nascer fui neuro-programada para espectro desse material, não apocalíptico. Mas previsível, na condição de projeção ao futuro! Aos homens leigos a ideia de transmissões do futuro, ou vidas do futuro para formatar o que para nós estar por vir, faz com que frequenciais determinem nossas ações, ciaram a imagem bíblica. Anjos, psicografias,10 mandamentos e vislumbradores foram alvejados por portais. Ser tida como promíscua, não faz de mim promíscua quando sofro curras e agressões por hipnose e biochips. Sou vítima e a minha vida nunca foi minha, com a Time Life implantada no brasil. Acordem estão usando a mídia para a tão presente mentira. Estou próxima dos 50 anos e são décadas de vida oferecida a orgia. A carne dos meus filhos também por insistência de vocês. Uma só casa no mundo todo com esse propósito.VEJAM o que nos causam, manipulam nossa vida para o sádico entretenimento de vocês!!!! BBB do crime encobre crime de curra. Não vejo ninguém que dá audiência ser currado ou agredido, nem meus pais que entregaram a nossa carne para a orgia do sucesso de múltiplos produtos. Não perdoo nada, nem ninguém! Vocês nunca perdoariam quem abusa de seus filhos!! Fabulam débitos com meu nome e transtornam minha vida financeira para justificar o crime e a me caluniar. Culpar a mim pelas ambições de ricos exploradores, transferir para mim a responsabilidades de catástrofes?!... COVARDES!!! Fica claro no filme que ela é vítima e apresentam como causadora de confusões.http://www.youtube.com/watch?v=7j8Ba9rWhUg

Metropolis (restoration trailer)
www.youtube.com
http://www.kino.com/metropolis/ Metropolis is a 1927 silent science fiction film directed by Fritz Lang and written by Lang and Thea von Harbou. Lang and von...